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BMEB W4011 Computational Neuroscience: Circuits in the Brain

Course Benefits

  Provides a straighforward theoretical foundation to computational neuroscience.
  Focuses on the intuitive understanding of information representation and neural coding.
  Enables the further exploration of key concepts in theoretical neuroscience.

Professor Lazar

  Interests in Computational Neuroscience: In Silico: Time Encoding and Information Representation in Sensory Systems, Spike Processing and Computation in the Cortex. In Vivo: Olfactory System of the Drosophila Melanogaster.
  Further information about the instructor is available under URL: http://www.ee.columbia.edu/~aurel.

Applicable Degree Programs

Most courses 4000-level and above can be credited to all degree programs. All courses are subject to advisor approval.


Lecturer: Professor Aurel A. Lazar
  Office hours: Mondays, 4:00 PM - 6:00 PM, EST, Room 819 CEPSR
  E-mail address: aurel "at" ee.columbia.edu
  Class Web Site: Offered by CourseWorks
TA: Yevgeniy Slutskiy
  Office hours: Wednesdays, 2:00 PM - 4:00 PM, EST, Room 804 CEPSR
  E-mail address: yevgeniy "at" ee.columbia.edu
Day and Time: Tuesdays, 6:50 PM - 9:20 PM
Class Location: 415 Schapiro CEPSR
Credits for course: 3 points
Prerequisites ELEN E3801 (Signals and Systems) or Biology W3004 (plus Matlab) or the instructor's approval
Description: Modeling Biological Neurons, The Hudgkin-Huxley Neuron, Modeling and Analysis of Ion Channels, Integrate-and-Fire and other Spiking Neuron Models, Stimulus Representation and the Neural Code, Time Encoding and Stimulus Recovery, Information Representation with Time Encoding Machines, Fast Algorithms for Stimulus Recovery, Elements of Spike Processing and Neural Computation, Modeling Synapses and Synaptic Transmission, Synaptic Plasticity and Learning Algorithms.
Recommended text(s): Daniel Johnston and Samuel Miao-Sin Wu, Foundations of Cellular Neurophysiology, The MIT Press, Cambridge, MA, 1995.
Reference text(s): Peter Dayan and L.F. Abbott, Theoretical Neuroscience, The MIT Press, Cambridge, MA, 2001.
W. Gerstner and W. Kistler, Spiking Neuron Models, Cambridge University Press, New York, NY, 2002.
Izhikevich E.M., Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting, The MIT Press, Cambridge, MA, 2007.
Christof Koch, Biophysics of Computation, Information Processing in Single Neurons, Oxford University Press, New York, NY, 1999.
F.M. Rieke, D. Warland, R. de Ruyter van Steveninck, W. Bialek, Spikes: Exploring the Neural Code, The MIT Press, Cambridge, MA, 1997.
Peter M. Trappenberg, Fundamentals of Computational Neuroscience, Oxford University Press, New York, NY, 2002.
Hugh R. Wilson, Spikes, Decisions and Actions, Oxford University Press, New York, NY, 1999.
Homework(s): 6, mostly writing or adapting simple Matlab code.
Paper(s): ---
Project(s) 2 major projects
Midterm exam: ---
Final Exam: Take-home exam is due on Monday, December 15, 2008, at 12 noon.
Grading: 1/5 homework, 2/5 for each project or
1/5 homework, 2/5 for best project and 2/5 final
Hardware requirements: Laptop for demos
Software requirements: Matlab (student version)
Homework submission: Mondays at noon - strict deadline.